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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4f78c75230bf4e2657af0c50e15a1e2743847d5e0f56f4267c905c2b7fc4a9' 
  AND token = 'PqQE4LPArBU1+hScsIetxFlOiUi0gipGe066MJjYRd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}