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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a08dc3b391b837d6def3efe1559ff9aea66e930c0102f65cbdf2e15c52d14bf0' 
  AND token = 'DryYxjWeA5YmqDx1x/HUhHfy4gnv+XsrQgcsOui1Klo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}