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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc1cffbee5fdb41d5b1fcded190354457df4903cb6240a4285753d175146e44' 
  AND token = 'NHvixLR6XI8Lj+1QRrxC1ifNQD3z5wNh0cqh5kmSjkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}