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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a0644ddf166f121be5a6ac1c9702cd45e0c3667bfd51f98d2c0f7911590cff' 
  AND token = 'ORuw0PqOB4q597WO8pz3pKAYFnbNGqnXjqlFZudbvf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}