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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8fe199b78f556c3849104460bf903411d6b11159d1203d33d675cf1f689c02' 
  AND token = '7SbnnxQjlPzZlSaUDbGkpFExXh9sUfDU25VQv/nhxDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}