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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21da0c61f580759005d54d205440aa9f4c2b5c939a9c467050ed1022c6708f68' 
  AND token = '0iIopdpaTd4IcIb9xyWlQQnmK2dCN612nBjTywMrH0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}