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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0eba63e3b9e62403e6b854780b721da40f6b580f2fdca0aa8d1018d1136132b' 
  AND token = 'e4vjOWvoUmwLZd2rhPcs+XlQLSPjak+GUvh0YE8n4qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}