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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd250fa13a11007467a3ce02a70538cdc01d645f1af4607106747493db3fcc0ee' 
  AND token = 'xYcaZeG3XWn8rYSd925s8x0K99zJnmjQq6rgU1/iiqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}