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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c287678af7c699897f6a295f98bf18df685319fbadf9b746a5286e8a67ed971d' 
  AND token = '6HMpXj6UQLpiW7d+09+vT8u0/E6zy28qyzn5lY4mpAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}