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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46eebbd424a1e99e12c510cac6be22fa767943d6dff286845115d6b2ff7f8a1d' 
  AND token = 'nXgaZ6MPP7Do+ijdWY0PL8eXirQjB7ow/3KtN13FA2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}