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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f8577c0d15c052d3d81da1ddf8f36cb3296d885ce3823487606239bd9b2791' 
  AND token = '3MSm6xANJPvS+k2yD/IC1jd1jPdWKeuRcBdK2wBQgMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}