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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c378201aef9be37f2628abae5d77e01668b0d7794664c26a6acb21b41f6da080' 
  AND token = 'XRf7okOKjQh86SmrOp4+ktu7yiNpX3kk8BtS/oS+TGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}