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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5650bcf10e7e45f171a21b4b035f77111ad9a8f57be75d64e2cff1175aa52a60' 
  AND token = 'FQdymSyim2qddorfjskhpCVArWb9SSUMcVn9I0T6gyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}