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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63db6900a48de8577036b9e9d6db4c5f81ea754729a4d4578bdd4b9873b99f9' 
  AND token = '+TFpFDohQ2C9jxNJSnG1pavnOIFqCznFTydQqne8Htk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}