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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bc2e38b8fe3b1f43b108a0676f60dea47a8179c7c153e948814a0d587b6892' 
  AND token = 'cMTV2ujuVZhgami6I7zLqMciIudHtbnA+03BEy35Yso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}