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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643309ce34cff7d69ebeebf3159a5095ca05293ec29a15aaf39dd3730e58e6b7' 
  AND token = 'Iw/j6GrBGt9fQkUj0es+O4b5xCH260bYaTfkRD1k/GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}