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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cada5f6f8c77f11507804597186f450c1aee9a44f14db7976b208f12bc72c0' 
  AND token = 'dljPh+oq4IYPBHRTJkkV50XDkXVQA+nRnuA6Bb+gQQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}