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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4019881ba33375fb0e36233817e6f75b07f3d0fdc1ed04ca9412f50b1de12e10' 
  AND token = 'EPMZA1ZlUuw6/1Sjvy8M958Pn5ZjK2MRmdfBXu8KfTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}