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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cf5f40fffb54f2c1ff348a4476c2b34ac3d47bbefd18819b2ee359320b6e08' 
  AND token = 'ZS+7xThfQzdrrDfypf+dsBOQStz+8XUAR7xH2CDy8BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}