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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50f75977cd8fb42a44b1835918e0ad9d19f835fd4e854074ba462831b576d45' 
  AND token = 'rYJRVo7JY0RHNBvjsMwM3TYp+BM0FUd5s61oxX5A6PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}