SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a894c0ac3e5005e3be547faf52d792e3123162d06bd995821c799bbfeb8947c' 
  AND token = 'QRJ4kkcn7l8h95WPr0OOJg4AgSJQ+SVn7tRgA3ynZvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}