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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1263defd90e5809b052aaa01df4b4cd3b26db4631acdcbb0011c64a73302d6d9' 
  AND token = 'B/oZrLcbnY6PVBMn0t7pGY6TUCsH3ngfWSUqanda4Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}