SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    1661, 255, 65, 1959, 1011, 1685, 1207, 
    1210, 1203, 1389, 1188, 1190
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "table_name": "cscart_product_prices",
      "access_type": "range",
      "possible_keys": ["usergroup", "product_id", "lower_limit", "usergroup_id"],
      "key": "product_id",
      "key_length": "3",
      "used_key_parts": ["product_id"],
      "rows": 12,
      "filtered": 3.367346048,
      "index_condition": "cscart_product_prices.product_id in (1661,255,65,1959,1011,1685,1207,1210,1203,1389,1188,1190)",
      "attached_condition": "cscart_product_prices.lower_limit = 1 and cscart_product_prices.usergroup_id in (0,1)"
    }
  }
}

Result

product_id price
65 68000.00000000
255 66000.00000000
1011 106000.00000000
1188 14500.00000000
1190 21000.00000000
1203 12500.00000000
1207 12500.00000000
1210 12500.00000000
1389 12500.00000000
1661 66000.00000000
1685 200000.00000000
1959 95000.00000000