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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c0f4db93347ba60fc3c732993c3465f3b981365f2b34e26261b84da30386f2' 
  AND token = 'GDHrUOm2EKswfvJoRtABIoMJ2Fhkj7vlXSbFJQbUc0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}