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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bfc030ceee9f12ff4e7609ad81da2726bf98d5c329b7d81072c98d56e9cd40' 
  AND token = '2wHpWYCuC302LwyHvSPhknA18xS8ig+24bC9bVO62GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}