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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bbd01e1abad9f4b132e0617798d313d06004477ba9e565425579ec27c135459' 
  AND token = 'thBKNYVZZn8IAlCs54tbiWfHQnS/QqTD+sEMa9/ltAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}