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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b2440cd153a252fcd2a470bc75012dafe62080ad022dadf42d510b71d0a6756' 
  AND token = 'Y+b9RA1GUoS1QbvfJ9pxa+xhCP3uNby5xfyQQeSuAb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}