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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b0ff50f1ee0f459e0468107aeb3ed2409bfb20939b2910b089c5421024b8c4' 
  AND token = '3uC/lgPdquhMIeosIlmZE6fNEhRKshatwKIow+MAXAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}