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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181ecd68b5eec7fa007889278bd1604281663b81fc0bc0482ec7956484e2ddbd' 
  AND token = '1JkD+LjC/k5AV/4RURpdT0o6u6dpvl6pGr2JSZjaR+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}