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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f49175fbdbb44d2ce5823a027be527daecd9a8458ac09b6205549cac8adf422' 
  AND token = 'rU8T1AMlmTyfL9/Xzw+rXxaRvhKSAOVTWsdCp97GH08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}