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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fbf395f460d0f2b6a521deb1a7f73cea01b21de1c5989cb1d56a15634e9eed' 
  AND token = 'rGKMKwtpaMyhIBr+qK9FpK3EndOjR/dtSp9TVYqoR9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}