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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e3626e28fcbc8fe799070a89e7b53e3442425e5a55070fce75eba3545317a9' 
  AND token = 'TqjdlRA8i0R75iv3E2YNqFRVpxlKyqAn0rFP1GsM2Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}