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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcef599b62496a2689db166ece61b55cd69f2157f479c7904b0c6ee470da9e25' 
  AND token = 'eVUk86LuQFaPuAdqzVsXO6s/sjqsSVa3KQOvdN1Ld3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}