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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65902a45d69a6671f2b0c55db817def17a80c57d89348da1bd3079ea755fb9bf' 
  AND token = 'kL03wI3cx0zrhUEX6H+JTlGOYQMZn2UOxgk+Ol2fEpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}