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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65037b0d4baf930b0ebf0af21c3b82be2061b2431b004792d6cf6366cc7bd06b' 
  AND token = 'cU6Z1wl8NSMpBMl9nAaOB4Hkrd0ODNLku/JxEKZEPxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}