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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122954445ed12cdd85c6b15db63c24b294105b15c23a45a30b80cd74490fa7f4' 
  AND token = 'JI40WzXHXz53EKIArolqN3U8U1zkBe7nM2vmFqlJnZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}