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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c391f4fc46aa30638746c56c401d118d3a56514a55efacd2a2c18a56dc7f62' 
  AND token = 'rXN7uh5KkpG2bM+14jO389qa5qdkf1Ef9ATH++cB/KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}