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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea0b9a601c56c3f021c071ff6b042b7daafa17c3f4917fe245bb249c914a5651' 
  AND token = 'lYrgq0U1kZDP2U/kPi38MCjHFUVRDrJKiRRrEti1IxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}