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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33db6552c188b3b5b024b9fa15b52e39b81dbf7a1e257b6ab5424e501333a0a' 
  AND token = 'mbAv448aNXO1g8I+JPjzjOb4ZR7lMxZpDcc2q42I6+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}