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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a693ae22afaf32ccbefc1bdf4e66c29c4d501095645e3e4be80f8bbb575b81' 
  AND token = 'EMA5yAeKS0dgdCd1V1S/t+G/rIcP1ZjbIIKlb8Js7LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}