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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1797e183f6595bb41663d403e99dd42be7edaacf2858d29d9e0d317016f7622' 
  AND token = 'S6y/RPg2cu04b11cxhM9UEanENVM3wNgHjoC/cxt4o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}