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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b6a1c3531d0e84f54941c17ec5c0022fb7847d12bbef9f4d328280ce771a29' 
  AND token = '+h7N2pn4UdNTuEAkDwZA6HIdPsWr9HI5HdPbfUB4rlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}