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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21da9ca14415b4a2f4211cb29f4b1bd287d3c1a9b711cc4aba3865139bb6c0a1' 
  AND token = 'GBxYrIY5yt3CK34GA8IvIrZclZ+i9JfpdgjFJq6Hc6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}