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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94d00d3250fd52f560e19bf56fdc8c010bd314e3c6bbb7b52a611ec57b98a199' 
  AND token = 'l5OTMIGOsm/sy5WUGofbtE5XBmIDy5r1bGqXjdzGps4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}