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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729b16e94d9cd5679eec285ceb08fedac468cb58ca7a217998861f21348f6142' 
  AND token = '6PDPYEa1Bk5CL6EOcANfzzqg2AMgfUQr8alEdz5yWoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}