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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1133eb10385f35bb64e1d76815d7226536d10f06ea7a1e6550afc1c64e6b49' 
  AND token = '6ArtaNcgkfX1U8XMysJ4L4LR0aIfWaO3I4TJypzcTIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}