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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1258df666b3604a4e91df3b6fc783359c2a2620e8cb023e57e3c800f74a9a1cf' 
  AND token = 'Sim3ziMJMx4lrM2cm2m29K2MxC6nVL2uJGs26bvTNN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}