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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d25ec589ad56febb9c60c640bddb8e1f53d96d277faf5eb3a86a3c5a46b2d4' 
  AND token = 'VGpCre/F4ocIlP+87M1fstkE24WTzAmTbpzYO587AxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}