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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d33bd4178e51a30af3ec812b0ba5530b4d1d287754b499bc61ad95d4ca2051' 
  AND token = '+A1XoVamEXYSyojtY/IHUvEB2P8GMFNXE8rJr+FOLO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}