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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dd3f4e3b2be2872d984e227c47b47014cfe5ee0d3f3f15412677faa17285289' 
  AND token = 'YowDTDwK87dUy196LmnQ2R+7NLRHj4kZuw35W2c81Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}